Just gonna drop off critique of the last 2 card suggestions (don't hate fellas, I just think critique is a valid form of suggestion):
-Cykadelic's card: the double edged idea I like, but in my humble opinion it should deal the same damage. With proper planning this leads to you getting rid of a super strong card of the enemy while only losing a minor creature, or - lose a minor creature of the enemy that has some added utility and not lose any of yours by targeting something with more health.
-Shizuyami's card: I'm still new and haven't tested PVP much, but as a Genesis player that did face the spam of AOE (winds of war or the 1 hp one) I can tell you that immunity is not required. You have other alternatives as to how this location work, that will also be much more beneficial without being 'over powered'. If you have a location that adds +3/+3 to each artificial being that is in play, you can easily control the rest of the outcomes with planning. If you really feel it's still needed that location can also restore health to all artificial beings at each turn (let's say 3 points). Also, I noticed that while the mass AOE tactic can affect us, if we don't rely solely on Unending Drones we can still do well, I prefer sacrificing Bad-Bots and other heavier creatures if possible, sure it's not as cost effective but you can play around that considering that mass AOE is expensive as well.
Thanks for reading.